Not academically; they're doing fine. It's just really hard to find your way to my office, and I suspect that some people who want to come to office hours are staring at elevators that don't even go to the basement and thinking, "What?" (Indeed, this post was interrupted by a student saying, "I just got lost for ten minutes trying to find this place.") Heaven knows that the other day, to get here from the fourth-floor-next-building-over office where my mailbox is, I eventually had to give up, go outside, and come in a different door.
Say what you will about Frank Gehry; whoever designed the J-shaped Nightingale/Holmes/Meserve/Whatever complex has a lot to answer for.